Nitrilotriacetic acid

  • 2-(Bis(carboxymethyl)amino)acetic acid
  • Triglycine
  • N,N-bis(Carboxymethyl)glycine
  • Triglycollamic acid
  • Versene NTA acid
  • Complexon I
FormulaN(CH2COOH)3
Structure
DescriptionOdorless white solid.
UsesChelating and sequestering agent.

Registry Numbers and Inventories.
CAS139-13-9
NIH PubChem CID8758
EC (EINECS/ELINCS)205-355-7
EC Classharmful, irritant
EC Risk PhraseR 45 22 36/37
EC Safety PhraseS 53 45
RTECSAJ0175000
RTECS class Tumorigen; Mutagen
UN (DOT)2811
Merck12,6675
Beilstein/Gmelin1710776
Beilstein Reference4-04-00-02441
Swiss Giftliste 1G-5307
Canada DSL/NDSLDSL
US TSCAListed
Austrailia AICSListed
New ZealandListed
Japan ENCS (MITI) Listed
Korea ECLListed

Properties.
Formula C6H9NO6
Formula mass 191.14
Melting point, °C 242
Boiling point, °C 498
Vapor pressure, mmHg 3E-11 (25 C)
Density 1.67 g/cm3
Solubility in water 1.3 g/L
pKa/pKb 1.84 (pKa)
Partition coefficient, pKow -1.76
Heat of vaporization 83.9 kJ/mol
Heat of combustion -2335 kJ/mol

Hazards and Protection.
Storage Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
Handling Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes. Avoid ingestion and inhalation.
Protection Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Disposal code 3
Stability Stable under normal temperatures and pressures.
Incompatibilities Strong oxidizing agents.
Decomposition Carbon monoxide, oxides of nitrogen, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C255
Fire fightingWear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Fire potentialThis material is probably combustible.
NFPAHealth2
 Flammability0
 Reactivity0

Health.
CarcinoginI-2B, N-2, CP65
Poison_Class4
Exposure effects Possible cancer hazard based on tests with laboratory animals. May cause kidney injury.
   IngestionMay cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause kidney damage. May be harmful if swallowed.
   InhalationDust is irritating to the respiratory tract.
   SkinDust may cause mechanical irritation.
   Eyes Dust may cause mechanical irritation.

First aid
 
   IngestionDo NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   InhalationRemove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear. DO NOT use mouth-to-mouth respiration.
   Skin Get medical aid if irritation develops or persists. Wash clothing before reuse. Flush skin with plenty of soap and water.
   EyesFlush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transportation
UN number2811
Response guide154
USCG CHRIS CodeNAA  
HS Code 2922 49 95 

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